Radioimmunoassay of angiotensin I, for estimation of plasma renin activity.
نویسندگان
چکیده
Submitters: Betty Lash and Norman Fleischer, Department of Medicine and the Baylor General Clinical Research Center, Baylor College of Medicine, 1200 Moursund, Houston, Tex. 77025 Evaluators: Andrew M. Michelakis, School of Medicine, Vanderbilt University, Nashville, Tenn. 37232 L. Rao Chervu, Albert Einstein College of Medicine, Yeshiva University, 1300 Morris Park Ave., Bronx, N. Y. 10461 Fred H. Katz, Univ. of Colorado Medical Center, 4200 E. 9th Ave., Denver, Cob. 80220
منابع مشابه
Theoretical approaches to estimation of plasma renin activity: a review and some original observations.
Performance of accurrate, reproducible, and interpretable assays for plasma renin activity and other components of the renin/angiotensin system in the clinical setting requires a clear understanding of the various reactions in the renin/angiotensin cascade and the nature of their interactions. Plasma renin activity, the rate of angiotensin generations from plasma incubated in vitro, is the most...
متن کاملEstimation of plasma renin activity by radioimmunoassay of angiotensin I.
The renin-angiotensin-aldosterone hor monal system has been shown to be involved in the pathogenesis of certain hypertensive disorders, notably primary aldosteronism, malignant hypertension, renovascular hy pertension and that induced by oral con traceptives. 1 " 7 Plasma renin assay has be come an important diagnostic tool for in vestigating these disorders. Previously, plasma renin activ...
متن کاملDevelopment of a Mass Spectrometry-Based Assay for Measurement of Angiotensin I and Plasma Renin Activity to Diagnose Secondary Hypertension
Supervisory Committee Dr. Christoph Borchers, Department of Biochemistry and Microbiology Supervisor Dr. Terry Pearson, Department of Biochemistry and Microbiology Departmental Member Dr. Patrick von Aderkas, Department of Biology Outside Member The renin-angiotensin-aldosterone system (RAAS) plays an essential role in maintaining plasma volume and arterial blood pressure by regulating angioten...
متن کاملPlasma renin activity in infants with congenital heart disease.
Plasma renin activity was estimated in 11 infants with severe congestive heart failure. The infants had congenital heart disease with left to right shunts and were receiving diuretic treatment. Plasma renin activity was measured by radioimmunoassay of generated concentrations of angiotensin I. The mean (SD) plasma renin activity was 84 (21) ng angiotensin I/ml/hour, which is considerably above ...
متن کاملThe effect of aspirin therapy on the plasma renin activity in myocardial infarction
In this study, the changes of renin system activity and the effects of aspirin therapy on the plasma renin activity ( PRA) in myocardial infarction were investigated. Fifty nine patients with myocardial infarction were selected. By suppressed in the former group which was statistically significant ( p<0.01).
متن کاملMeasurement of plasma renin activity by semi-micro radioimmunoassay of generated angiotensin I.
A semi-micro method for determination of plasma renin activity (PRA) by radioimmunoassay of generated angiotensin I (AI) is described. The method permits measurement of PRA on 250 mul of plasma without loss of specificity, sensitivity, accuracy or preision. The small sample size has considerable application in terms of investigation of infants and young children. A reference range was establish...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Clinical chemistry
دوره 20 5 شماره
صفحات -
تاریخ انتشار 1974